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The True Source of
Super piggyBac®

When viral vectors and CRISPR just don’t cut it.

Super piggyBac—Engineered for Performance

Hera BioLabs is the exclusive licensed provider of the patented Super piggyBac system for drug discovery research, diagnostics, synthetic biotechnology and agricultural applications. When performance matters—and freedom to operate is essential—partner with the team that brings over a decade of experience and validated protocols.

How piggyBac Works

Step 1: Clone cargo into transposon vector

Step 2: Co-transfect Transposon and Transposase into cells.

Step 3: Transposase cuts out cargo and pastes into random TTAA sites.

Step 4: Screen clones for desired insert.

Step 5: Use Excision-only piggyBac for Footprint-Free gene editing. (optional)

Super piggyBac is a next-generation protein engineered transposase that outperforms other technologies in stable gene integration and expression, cargo size, and seamless excision. Developed through protein engineering and protected by both patents and trademarks, Hera has also developed a unique manufacturing process that results in even higher activity with its optimized mRNA Super piggyBac transposase.

Features of super piggyBac

  • Stable integrating of genetic cargo ranging from small to exceptionally large sizes (200kb or more)
  • Superior transposase efficiency across diverse cell lines and species
  • Integration into open chromatin regions ensures stable and high-level gene expression.
  • No excision scars
  • IP license rights—only from Hera

Super piggyBac is Validated for Commercial Research and Product Development In:

The Industry Standards for Stable
Gene Insertion and Expression

piggyBac has been featured in 800+ papers including the high-impact publications below.

See how Hera’s technology and staff are assisting researchers globally in solving complex problems and producing robust data.

Shop Gene Editing Reagents

Super piggyBac Starter Kit

Designed for first-time super piggyBac evaluations

CATALOG # DESCRIPTION AMOUNT ORDER
R03
D02
D01
D04
Test super piggyBac transposase in mRNA (SPB-100) and plasmid DNA (SPB-D25) formats, alongside transposons with piggyBac ITRs, core insulators, and MCS for cargo insertion (SPB-007) or MCS with GFP and Puro selection (SPB-012).
Transposases 25 µg
Transposons 10 µg
Contact Us

Super piggyBac Products

CATALOG # DESCRIPTION AMOUNT ORDER
R03
Super piggyBac transposase mRNA
25 µg Contact Us
D02
Super piggyBac transposase DNA
25 µg Contact Us
D03
Excision-only super piggyBac transposase DNA
25 µg Contact Us
D01
Empty piggyBac transposon base vector with multiple cloning site (MSC)
10 µg Contact Us
D04
piggyBac transposon containing a CMV promoter-MCS-SV40PolyA for cloning gene of interest and a GFP-Puro selection cassette.
10 µg Contact Us

All reagents are provided at a 1 ug/ul concentration per vial. Shipping for RNA reagents will be on dry ice. Shipping for DNA reagents will be ambient temperature or on ice. Transposases are designed for direct use and cannot be propagated.

Why Licensing Matters

Super piggyBac® is not open-source. It is protected by U.S. and international patents and is a registered trademark. Hera BioLabs, a Demeetra company, is the sole licensed provider of Super piggyBac for research, drug discovery, synthetic biotechnology and other applications. Partnering with us enables confident internal research and provides a clear path to commercializing your engineered cell and animal models.

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Insights From Hera’s Team

Learn from Industry experts with thought leadership content about Hera’s piggyBac technology.

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